Environmental risk assessment of commonly used anti-cancer drugs
نویسندگان
چکیده
This study has been focused on the commonly used anti-cancer drugs (ACDs) in Turkey terms of environmental toxicity, behaviors sewage treatment plants (STPs), biodegradability and physicochemical properties. For this purpose, EPI Suite, estimation programme, by employing BCFWIN, KOWWIN, KOCWIN, HENRYWIN, AEROWIN, ECOSAR, BIOWIN, STPWIN suites. Among 13 selected ACDs, Tamoxifen found as most risky pharmaceutical due to its high Predicted Environmental Concentration (PEC) / No Effect (PNEC) value (2.96350). Even if total removal efficiency is rather (97.24%), considerable portion (71.50%) retained sludge leading compose hazardous waste. Additionally, parameters, log Kow (6.30), Kd (62230 L/g), Koc (4.400) BCF (6689 L/kg), calculated for indicate that highest sorption potential tends bioaccumulate organisms, respectively.
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ژورنال
عنوان ژورنال: Cumhuriyet Science Journal
سال: 2021
ISSN: ['2587-2680', '2587-246X']
DOI: https://doi.org/10.17776/csj.866883